Eric Leininger connected on eight from long distance en route to 23 points as Cedarville won its fifth straight. The Yellow Jackets improved to 6-1 overall and 2-0 against the AMC South.
The Redmen, on the other hand, fell to 3-4 and are still winless in conference play.
Freshman Danny Frank scored 11 to pace Rio Grande. Will Norwell added nine while Chris Dinwiddle and Joe Mendenhall chipped in eight apiece.
Rio Grande is at Notre Dame on Saturday.